10: Splice
An indie sci-fi flick which originally did the festivals last year, centers around two scientists (played by Adrien Brody and Sarah Polley), who recreate a creature in a lab, which eventually manages to escape. Release date: June 4.
9: Despicable Me
An animated comedy about the evil mastermind Gru (voiced by Steve Carell), who draws plans to steal the moon. However, when he meets three orphan girls, things change. Release date: July 9.
8: The Last Airbender
M. Night Shyamalan, who’s last few films haven’t been much to cheer for, brings the movie adaptation of The Last Airbender, an action-adventure fantasy with some impressive visual effects. This is also Shyamalan’s first film which he didn’t create himself, but rather, which he adapted from another source (anime). Release date: July 2.
7: The Cross
Little is known about The Cross, only that it centers around a man who “crosses a border that’s never been crossed before”. From the official artwork of the film, it looks quite interesting, and we expect something great from this film, considering it’s written and directed by Andrew Niccol — writer/director of Gattaca and Lord Of War. Release date: December.
6: Predators
Another take on the Predator franchise, this time with a few decent actors in the form of Adrien Brody and Lawrence Fishbourne, who are part of a group of soldiers hunted by a pack of Predators. Release date: July 9.
5: Resident Evil: Afterlife
Paul W.S. Anderson returns to the Resident Evil franchise with Mila Jovovich, for another round of monster slaying, this time in 3D. Release date: September 10.
4: Tron Legacy
The remake/sequel of the classic sci-fi movie TRON will be coming later this year, where a virtual world worker sets off to eliminate the Master Control Program, played by none other than Jeff Bridges. Release date: December 17.
3: Iron Man 2
There’s not much to say about this: the sequel to one of the biggest hits of 2008, Iron Man. Expect the sequel to up the ante pretty much across the board. Release date: May 7.
2: Prince of Persia: Sands Of Time
Based on the popular video game of the same name, Prince of Persia: Sands Of Time starts Jake Gylenhaal as the prince who teams up with a princess in order to fight an evil ruler, played by none other than Ben Kingsley. Release date: May 28.
1: Inception
Christopher Nolan takes a break from Batman to bring this original sci-fi film, which, as Nolan describes it, “tells the story of Cobb, an agent who has a team of people who have access to a technology that allows them to enter people’s minds through their dreams”. Release date: July.
(source - santabanta forum)